Skip to main content
Fig. 3 | Biomarker Research

Fig. 3

From: The combinatorial approach of laser-captured microdissection and reverse transcription quantitative polymerase chain reaction accurately determines HER2 status in breast cancer

Fig. 3

Assessment of HER2 status using RT-qPCR, FISH and IHC. Relative expression levels of HER2/EEF1A1 in arbitrary units (AU) were calculated for (a) total tumor tissue and (b) microdissected tumor tissue and compared to the HER2 status as determined by IHC and FISH. Mean values and the 95 % confidence interval for the mean is separately indicated for HER2- positive and negative samples. Significantly higher HER2 mRNA levels were detected in IHC/FISH HER2-positive samples with p < 0.001 and p < 0.0001 for total FFPE tissue and microdissected FFPE tissue, respectively

Back to article page

Biomarker Research

ISSN: 2050-7771

Contact us