Skip to main content

Table 1 Study population characteristics

From: Multiple regulatory events contribute to a widespread circular RNA downregulation in precancer and early stage of colorectal cancer development

 

Type of lesion

 

Tumor (N = 96)

Adenoma (N = 27)

P-value

Age Mean (SD)

69.1 (± 10.1)

69.6 (± 11.6)

0.73

Sex (%)

0.83

 Male

56 (58.3%)

15 (55.6%)

 

 Female

40 (41.7%)

12 (44.4%)

 

BMI

0.06

 Mean (SD)

26.5 (± 5.3)

24.4 (± 3.8)

 

 Missing

10 (10.4%)

3 (11.1%)

 

Smoking habit (%)

0.71

 Never

44 (45.8%)

11 (40.7%)

 

 Former

12 (12.5%)

5 (18.6%)

 

 Smoker

31 (32.3%)

9 (33.3%)

 

 Missing

9 (9.4%)

2 (7.4%)

 

Stage (%)

 nAA

-

3 (11.1%)

 

 AA

-

24 (88.9%)

 

 0-I

26 (27.1%)

-

 

 II

32 (33.3%)

-

 

 III

31 (32.3%)

-

 

 IV

3 (3.1%)

-

 

 Missing

4 (4.2%)

-

 

Mucinous status (%)

 nmCRC

70 (56.9%)

-

 

 mcCRC

20 (16.2%)

-

 

 mCRC

6 (4.9%)

-

 

 Missing

27 (22%)

-

 

CMS (%)

 CMS1

8 (8.3%)

-

 

 CMS2

27 (28.1%)

-

 

 CMS3

24 (25.0%)

-

 

 CMS4

23 (24.0%)

-

 

 Missing

14 (14.6%)

-

 

APC mutational status (%)

0.24

 Mutated

55 (57.3%)

18 (66.7%)

 

 Wild-Type

38 (39.6%)

6 (22.2%)

 

 Missing

3 (3.1%)

3 (11.1%)

 

KRAS mutational status (%)

1.00

 Mutated

25 (26.0%)

7 (25.9%)

 

 Wild-Type

68 (70.8%)

18 (66.7%)

 

 Missing

3 (3.2%)

2 (7.4%)

 
  1. BMI Body Mass Index, nAA non-advanced adenoma, AA advanced adenoma, CRC colorectal cancer, CMS Consensus Molecular Subtype, nmCRC non mucinous CRC, mcCRC CRC with mucinous component (5%−50%), mCRC mucinous CRC (> 50%), SD standard deviation