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Table 3 Analyzed cohorts and public datasets

From: Multiple regulatory events contribute to a widespread circular RNA downregulation in precancer and early stage of colorectal cancer development

Data

Type of data

Source

Adjacent tissue samples

(n)

Adenoma tissue samples

(n)

CRC tissue samples

(n)

Cohorts

RNA-Seq

COLOBIOME cohort (Zwinsová et al., 2021)

-

-

159

This study

123

27

96

Public datasets

GSE156451

80

-

80

GSE142279

20

-

20

GSE95132

10

-

10

GSE74602

30

-

30

GSE41657

12

-

25

GSE20916

44

-

46

44

45

-

GSE8671

32

32

-

GSE77953

16

20

-

GSE4183

8

15

-

TMECircDB/GSE221240

8

-

6

Li et al., 2024 (Supplementary material)

30

-

30

NanoString (microarray-based)

GSE233799

10a

-

10b 

Single-cell RNA-Seq

GSE132465

10

-

25

  1. a = Normal epithelium (n = 5); Normal stroma (n = 5); b = Tumor stroma (n = 5); Tumor (n = 5)
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Biomarker Research

ISSN: 2050-7771

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