Fig. 2

Comparison TMT analysis of proteomic sequencing between control and EAC mouse bladder tissues. (A) A two-dimensional scatter plot of the principal component analysis (PCA) distribution of all samples by using quantified proteins. (B) Box plot of the relative standard deviation (RSD) distribution of repeated samples. (C) Heatmap of Pearson correlation coefficients for all quantified proteins between each pair of samples (n = 3). (D) Basic statistical images of the mass spectrometry results. (E) Volcano plot of proteins differentially expressed between the EAC and the control group. (F) Column chart of the distribution of differentially expressed proteins between the EAC and control group. (G) Heatmap plot of the top 10 upregulated genes in the EAC group (n = 3). (H-K) GO and KEGG enrichment analyses of the DEGs in the EAC group