Fig. 1
From: IL1RAP is an immunotherapeutic target for normal karyotype triple-mutated acute myeloid leukemia
NKt-AML surfaceome enrichment and pipeline analysis. A Leucegene AML surfaceome cohort characteristic comparison between NKt-AML and other primary human AML specimen. B Schematic representation of NKt-AML antigen selection pipeline. C Comparison of protein intensity between NKt-AML (n = 12) and other (n = 88) specimens of the Leucegene AML surfaceome cohort. FC: fold change in protein intensity. Red bars represent proteins with log2FC ≥ 1. Highlighted are candidate antigens (CTSG, ADGRG5, IL1RAP) and proteins overexpressed (ADGRG1) or underexpressed (CD34) by NKt AML