Fig. 2

PAQR5 is highly enriched in tumor cells to drive tumor progression. A, B UMAP plot of broad cell clusters and major cell clusters. C, D The expression distribution of PAQR5 in HCC cell clusters. E The proportion of each cell clusters in the PAQR5 positive/negative group. F PAQR5 gene expression across various cell lineages. G, H, I The distribution of spatial tumor micro-environment and PAQR5 expression. J, K, L Differences in PAQR5 expression between malignant and normal regions